Interested in Joining?

We’re so glad you are interested in our research! Before you reach out, read our social contract here that covers lab expectations and the lab culture to make sure we are a good fit.

Interested graduate students can come to IU Bloomington via either the Microbiology, Genome, Cell and Development, or the Evolution, Ecology, and Behavior programs. Check out those links and contact PI Newton (irnewton at indiana.edu) and get the conversation started.

We are always interested in motivated postdoctoral fellows to join our team. Currently, we have two postdoctoral research opportunities available.

Postdoctoral positions in host-microbe epitranscriptomics:

Successful host-associated microbes sculpt host cell biology in ways that are useful to them. Often, these changes in host biology alter the ability of other microbes to colonize, protecting the host niche for the first microbe. For example, colonization of insects with Wolbachia endosymbionts can preclude infection by viruses. This fact has led to the deployment of Wolbachia-infected mosquitos across the globe to limit the transmission of vectored diseases. We have identified RNA modifications induced by Wolbachia that directly alter Drosophila cell biology and affect the ability of viruses to colonize. Wolbachia upregulates a host methyltransferase to limit virus replication and our preliminary data suggest that the virus genome itself is modified in a Wolbachia infected cell, altering mRNA stability. These data lead us to ask “How does a microbial symbiont alter the epitranscriptomic landscape of host cells?” The ideal candidate will have experience in Drosophila, molecular virology, and/or bioinformatics.  The candidate will be trained in molecular virology, and the use of direct sequencing approaches (PacBio and ONT) to identify modified nucleotides.

A Ph.D. in microbiology, virology, bioinformatics, entomology, or a related field is required. The position will be funded for three years, with the potential to extend for an additional year. Salary will be commensurate with experience, and full benefits are included.

To apply, please submit (i) a letter of application, (ii) a full CV, (iii) a statement of research interests, and (iv) contact information for three references electronically to https://indiana.peopleadmin.com/postings/9951. For best consideration, please apply by October 31, 2020. Expected start date can be as soon as January 1, 2021 but is flexible. Inquiries about the position can be directed to Irene Newton (irnewton@indiana.edu).

Postdoctoral position in protective symbiosis in the honey bee:

The alarming and dramatic decline of the honey bee is likely due to the influence of important environmental stressors on honey bee health, productivity, and longevity. These stressors include limited floral resources (nutritional stress), parasites and pathogens (immune stress), and exposure to fungicides and pesticides (chemical stress). We have discovered that a bacterial symbiont of honey beesprotects against one of these significant stressors: fungal pathogens. Our preliminary data suggest that the symbiontsecretes antifungal metabolite(s) that protects bee brood from fouling; both in vitro assays and larval infection experiments support this conclusion. This proposed project aims to characterize how this symbiont protects bees. How did this trait evolve across the phylogeny of bee-associated and flower-associated alphaproteobacteria? And what is the identity of the antifungal metabolite? The ideal candidate will have experience in bees, microbiology, and/or bioinformatics.

A Ph.D. in microbiology, virology, bioinformatics, entomology, or a related field is required. The position will be funded for three years, with the potential to extend for an additional year. Salary will be commensurate with experience, and full benefits are included.

To apply, please submit (i) a letter of application, (ii) a full CV, (iii) a statement of research interests, and (iv) contact information for three references electronically to https://indiana.peopleadmin.com/postings/9979. For best consideration, please apply by November 10, 2020. Expected start date can be as soon as January 1, 2021 but is flexible. Inquiries about the position can be directed to Irene Newton (irnewton@indiana.edu).

In addition, we are also looking for an hourly research associate to join the group. If you want an opportunity to learn about genetics, microbiology, microscopy, and genomics, contact us!

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